Mitochondrial-derived peptide regulating cellular energy.
MOTS-C is a 16-amino-acid peptide encoded within mitochondrial DNA, studied for its role in metabolic homeostasis.
Activates AMPK signaling and translocates to the nucleus to regulate adaptive stress-response genes.
Peptide engages target receptor with high affinity.
Downstream intracellular pathways activate.
Gene expression and protein synthesis shift.
Measurable change in the studied biomarker.
Daily MOTS-c administration during HFD challenge with glucose-tolerance and insulin assays.
Prevented HFD-induced obesity and reversed insulin resistance via AMPK activation.
Examined MOTS-c as an exercise-induced regulator of muscle homeostasis in aging.
Restored running capacity and grip strength in aged mice to near-young levels.
Metabolomic profiling under MOTS-c treatment with insulin-sensitivity assays.
Improved insulin sensitivity correlating with shifts in lipid and amino-acid metabolites.
Store lyophilized at -20°C, protect from light.
Strictly for in-vitro laboratory and research investigations.
Not approved for diagnostic, therapeutic, or veterinary application.
Handling restricted to licensed researchers and laboratory staff.
Warning — MOTS-C is supplied solely for legitimate laboratory research. Any administration to humans or animals is strictly prohibited and may violate federal, state, or local law. By purchasing, the researcher accepts full responsibility for safe handling, storage, and lawful use.
